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募集終了
更新日 : 2026/01/27 募集終了日 : 2026/05/29
募集終了
更新日 : 2026/01/27
募集終了日 : 2026/05/29

勤務地 : Kanto district - Tokyo

公開開始日 : 2026/01/27

Call for a Postdoctoral Fellow for Proteostasis Lab at Keio University WPI-Bio2Q (PI Nadinath Nillegoda, PhD)

D126011606

Private university

Keio University

研究分野 : Others - Others - Human biology, Microbiology, Cell biology(Protein damage and cell repair), Structural biology, Molecular biology(Primate proteostasis, Protein disaggregation), Microbiome, Neural science, Immunology, Oncology, Genome science, Pharmacy, Quantum computing science, Computer science, Information science, Artificial intelligence

Researcher/Postdoc level : Contract employee - Nontenured - Non-tenure track - Probationary period absent

業務内容

  • 募集の背景、プロジェクトの説明

    Our laboratory investigates proteostasis network pathways that safeguard cellular and tissue integrity following protein damage. A central focus of the group is understanding how these pathways promote cellular repair, tissue resilience, and organismal health during aging. We are pioneers in the emerging field of primate proteostasis, and were the first to examine how primate-specific adaptations in protein quality control networks influence cell repair mechanisms and contribute to human disease, protein aggregation, and age-related decline.

    Transplantation biology is a cornerstone of modern medicine with profound implications for healthy aging. The long-term success of cell and tissue transplantation depends not only on immune compatibility, but also on the intrinsic ability of transplanted cells/tissue to withstand proteotoxic stress encountered during isolation, engraftment, and long-term tissue integration. Impaired proteostasis severely compromise transplantation outcomes and may directly limit graft longevity and function. Understanding and enhancing cellular resistance to protein damage therefore represents a fundamental opportunity to improve transplantation success and durability, with broad implications for regenerative medicine and age-related disease.

    In close collaboration with world-renowned clinicians and scientists at Bio2Q and Keio University School of Medicine, our group is leading efforts to modulate cell and protein repair pathways to enhance cell/ tissue transplantation outcomes. Our work explores a novel and transformative dimension of transplantation biology, with the potential to significantly improve the longevity and resilience of transplanted biologics.

    https://www.bio2q.keio.ac.jp

  • 仕事内容・職務内容

    We are seeking a highly motivated and skilled Postdoctoral Fellow to lead this innovative research program at the interface of proteostasis and transplantation biology. The successful candidate will have strong expertise in stem cell biology, cell/tissue transplantation biology, advanced imaging, and animal (mouse) work. This position offers a rare opportunity to define a new research direction with high translational relevance, enabling rapid and impactful discoveries that could substantially improve transplantation outcomes and promote healthy aging.

    The Postdoctoral Fellow will work closely with the Principal Investigator and engage in active collaboration with an interdisciplinary team of clinicians and basic scientists. These collaborations provide access to state-of-the-art technologies, experimental systems, and clinical perspectives, allowing the candidate to acquire valuable skills and establish a strong independent research profile.

  • 配属部署

    Existing departments

    Professor Nadinath Nillegoda’s Lab, Keio University WPI Human Biology-Microbiome-Quantum Research Center (Bio2Q)

Keio University

職種

  • Researcher/Postdoc level

研究分野

  • Others - Others

    Human biology, Microbiology, Cell biology(Protein damage and cell repair), Structural biology, Molecular biology(Primate proteostasis, Protein disaggregation), Microbiome, Neural science, Immunology, Oncology, Genome science, Pharmacy, Quantum computing science, Computer science, Information science, Artificial intelligence

給与

  • Annual Salary : 6 million yen ~ 7 million yen

    The annual salary will correspond to years of experience, ability, and performance.
    Model annual salary: 6,000,000 – 7,000,000 JPY

勤務時間

  • Working hours :08:30-17:00

    Break time :11:30-12:30

    Holidays : Days off include Sundays, national holidays, year-end/New Year holidays, and Keio University holidays (January 10, etc.).

    Overtime and other explanations : Working on Sundays and holidays may sometimes be required.

募集要項

応募資格

  • 応募に必要な学歴・学位

    Others

    Applicants must have been awarded a PhD and possess experience e.g. Stem cell biology, tissue repair/ transplantation biology and mouse model development.

  • 説明

    Research accomplishments: A good track record of research achievements. A first-author research article in a reputable journal is recommended. Candidates with first-author manuscripts currently in review will also be equally considered.

    Expert knowledge & skills: Demonstrated expertise in areas related to animal (mouse) experimentation, cell biology (ideally stem cell biology), cell/tissue imaging, cell/tissue repair/transplantation. Having exposure in proteostasis will be advantageous, but NOT necessary.

    Interest & motivation: A strong interest in the research outlined and the ability to independently design, execute, and analyze experiments, including animal experiments.

    Communication skills: Verbal and written communication skills in acceptable level of English are essential, as the candidate will be required to present findings to both internal teams and external collaborators.

    Collaboration & coordination: Excellent interpersonal skills and the ability to coordinate and collaborate effectively with other research teams, both within and outside the institution.

    Basic computer skills: Proficiency in standard computer applications and experience with data analysis software.

    Adaptability & problem-solving: The ability to think critically and independently, while adapting to new challenges and solving complex problems in experimental design and execution.

    Passion for career development: We are committed to the professional growth of our postdoctoral fellows. The candidate should have a clear interest in pursuing a successful academic or industry career and actively engage in career development opportunities.

    Organizational skills: Ability to manage multiple tasks and deadlines efficiently, while maintaining attention to detail in experimental protocols and data management.

雇用形態

  • Contract employee

契約期間

  • Nontenured - Non-tenure track

    (1) The contract is a three-year fixed-term employment contract and is subject to review each fiscal year. The contract is eligible for renewal based on performance and mutual agreement between employer and employee.
    (2) The renewable term is subject to change depending on the continuation of the WPI program, Bio2Q's management situation, budget situation, and other factors. In principle, the contract will not be renewed beyond the age of 65.

    Probationary period absent

勤務地

  • 〒160-8582 Tokyo Shinjuku-ku, Shinanomachi

    The successful applicant will work at the host laboratory within the Bio2Q research center located at 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.

待遇

  • 各種制度

    Transportation expenses : available

  • 加入保険

    Employees' Health Insurance : available

    Employees' Pension Insurance : available

    Worker's accident insurance : available

    Employment insurance : available

応募上の配慮

  • 面接実施に関しての配慮（海外など遠方にお住まいの方、他）

    For those unable to come in person, interviews may be conducted online.

採用人数

    1 person(s)

  • 求人内容補足説明

    Start date: The candidate must be ideally available to start in early-mid 2026. The exact dates are negotiable.

募集期間

  • 2026/01/27~2026/05/29 Deadline for receipt

    Selection process will be conducted on first-come-first-served basis and it will be closed once we find an appropriate candidate.

応募方法

  • 応募書類

    Application Form : Online Submission
    All applications must be submitted in English.

    Other online application forms
    *All applications must be submitted in English.
    1. CV
    2. List of research activities, including full list of publications, achievements, etc.
    3. Motivation letter including a description of how you plan to contribute to Bio2Q.
    4. Recommendation letter(s)

  • 応募書類の返却

    We will dispose of all application documents responsibly.

  • ※募集期間外です。

JREC-IN Portal Web応募
Not available
電子メール応募
Accept
nadinath.nillegoda(at)keio.jp
※(at)を@に変更して送信してください。
求人機関Web応募
Not available

公募のURL

選考・結果通知

  • 選考内容

    Applicants who pass the initial application-based screening will be interviewed in English. Applicants will be responsible for travel and accommodation expenses incurred during the interview selection process.

  • 結果通知方法

    We will notify you of the results of your selection by email.

連絡先

Keio University

Office of Research Development and Sponsored Projects, WPI (Bio2Q)

Personnel and Public Relations Team

bio2q_recruiting(at)info.keio.ac.jp

※(at)を@に変更して送信してください。

備考

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