Detailed information
Work location : Kanto district - Ibaraki
Date of publication : 2025/05/21
Seeking a Postdoctoral Researcher or Research & Development Scientist (T25001)(Drug Discovery Genetically Modified Animal Platform Unit)
D125051394
RIKEN
Research field : Life Science - Animal life science | Life Science - Genome biology | Life Science - Laboratory animal science | Life Science - Genetics | Life Science - Medical biochemistry
Researcher/Postdoc level : Contract employee - Nontenured - Non-tenure track - Probationary period present
Job description
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Background of the recruitment and description of the project
Our research unit utilizes disease model mice available in the BioResource Research Center to evaluate in vivo relevance of candidate causative factors, thereby contributing to drug discovery and medical research. By applying genome editing technologies, we generate genetically engineered mouse models that closely reflect human disease conditions by incorporating patient-relevant genetic modifications to enhance clinical predictability. Through the development of innovative disease model mice and the creation of novel drug discovery seeds, we aim to translate disease research into medical and societal benefits.
Keywords: disease model mouse, drug discovery, genome editing, genetic modification, phenotypic evaluation, gene expression, genetics -
Work content and job description
This position involves the development and phenotypic analysis of disease model mice to investigate the functions of disease-associated genes and validate drug target candidates. Genome editing technologies such as CRISPR/Cas9 are used to knock-out disease-related genes or to knock-in human pathogenic variants into mice. Phenotypic evaluations of the generated disease model mice include immunostaining and histopathological analysis of tissue sections, clinical assessments such as blood and urine tests, and molecular analyses such as gene and protein expression profiling. Basic knowledge of genetics and experience in laboratory animal handling are required for genetic management of mouse strains and experimental design. For clinically relevant models, further studies will be conducted to elucidate disease mechanisms and to explore therapeutic potential through in vivo drug testing.
The job description may be changed during the contract period or upon contract renewal to the extent described above. -
Assigned department
Existing departments
Drug Discovery Genetically Modified Animal Platform Unit, RIKEN BioResource Research Center
Job type
- Researcher/Postdoc level
Research field
- Life Science - Animal life science
- Life Science - Genome biology
- Life Science - Laboratory animal science
- Life Science - Genetics
- Life Science - Medical biochemistry
Wages
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Annual Salary : 3 million yen ~
Salary will be an annual salary based on experience, ability, and performance, and will consist of a base salary and a variable salary. The variable salary will be determined each fiscal year based on experience, ability, and performance. The monthly base salary is 327,200 JPY as of April 1, 2025 for a Postdoctoral Researcher, 384,000-458,500 JPY for a Research & Development Scientist. The monthly base salary and variable salary are subject to change due to amendments to RIKEN regulations. Discretionary work, commuting and housing allowances will be provided. Social insurance will be applied.
The approximate amount of annual salary at the time of employment:
The monthly salary including discretionary work allowance at the time of employment will be more than 367,925JPY for Postdoctoral Researcher and 459,565 JPY for Research & Development Scientist.
Working hours
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Working hours :09:00-17:20
Break time :12:00-12:50
Holidays : Days off include public holidays, New Year's holidays (Dec. 29 - Jan 3), and RIKEN Foundation Day.
Paid leave includes annual paid leave (up to 20 days depending on the month of employment), special paid leave (childcare, family nursing care, etc.), and work life balance holidays (up to 7 days depending on the month of employment).Overtime and other explanations : This position falls under the specialized duties discretionary work system; one working day will be calculated as 7 hours and 30 minutes.
Application requirements
Qualifications
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Education and Degree Requirements
Ph.D. / Doctor
The candidate should possess a doctoral degree in a related field (or expect to obtain by the start date), and preferably have research experience using animal models.
1. Postdoctoral Researchers should have less than 5 years since acquiring their PhD (Those who expect to have their PhD by the time they are hired are also eligible)
2. Research & Development Scientists should have 5 years or more research experience from acquiring their PhD
3. Understand the importance of bioresource infrastructure projects as essential research infrastructure and have a strong desire to carry out those projects, along with being able to tackle them autonomously and proactively.
Employment Type
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Contract employee
Postdoctoral Researcher or Research & Development Scientist
Contract period
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Nontenured - Non-tenure track
1. Both positions are fixed term contract employees with single fiscal year contracts. Following an evaluation, they may be re-contracted up to June 30, 2028.
2. RIKEN may adjust the above maximum period of renewability based on a) the employee’s abilities, workload at the time of contract completion, performance and work attitude and b) the continuation of the employee’s center, laboratory or project and RIKEN’s management situation and budget at the time. In principle, employment contracts will not be renewed for individuals older than 70 years.Probationary period present
In principle, the first two months of employment is considered a trial period.
There is no change of working conditions.
Work location
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305-0074
Ibaraki
3-1-1 Koyadai, Tsukuba,
RIKEN Tsukuba Campus
RIKEN may order the employee to change work locations, if necessary.
Compensation
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Various systems
Pay increase system : Salary will be an annual salary based on experience, ability, and performance, and will consist of a base salary and a variable salary. The variable salary will be determined each fiscal year based on experience, ability, and performance.
Transportation expenses : available
Others : Mandatory membership in the RIKEN Mutual Benefit Society (RIKEN Kyosaikai).
There are also additional leave systems such as maternity leave, childcare leave, and family nursing care leave. -
Insurance
Employees' Health Insurance : available
Employees' Pension Insurance : available
Worker's accident insurance : available
Employment insurance : available
Others : available
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Measures for preventing passive smoking at the workplace
Smoking is entirely prohibited on site.
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Supplementary explanation of compensation
RIKEN may require changes of responsibilities, job category, and workplace based on RIKEN regulations due to management decisions, budgetary situation, and organizational restructuring.
RIKEN is actively undertaking initiatives to promote gender equality and diversity, and moving forward with the establishment of a diverse and vibrant research environment. If multiple candidates are found to have the same aptitude following a fair assessment, active efforts will be made to recruit female candidates.
*Also, eligible for an exemption from repayment for category 1 scholarship loans provided by the Japan Student Services Organization before fiscal year 2003, and eligible applying for the MEXT Grants-in-Aid for Scientific Research (Kakenhi).
*RIKEN has a work-from-home system, but this position requires attendance at the work location. Therefore, the work-from-home system is not available for this position, in principle. For more information, please get in touch with the hiring staff at brc-jinji-ABC-@ml.riken.jp
Application Considerations
Number of hired
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Description
Job title
Postdoctoral Researcher or Research & Development Scientist : 1 position
Postdoctoral Researcher
The Postdoctoral Researcher position is one in which the researcher independently does their own research under the guidance of a higher ranking staff member. You will be laying the foundation to advance your research autonomously as a researcher in the future.
Research & Development Scientist
As a Research & Development Scientist, you will possess definite experience and outcomes and autonomously carry out research projects while consulting with your supervisor.
1 person(s)
Hiring date : 2025/11/01
Starting date : 2025/11/01
Application period
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2025/05/21~2025/07/01 Deadline for receipt
Deadline
July 1, 2025 (application to reach RIKEN by this date)
Application method
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Attached documents
Application Form : Online SubmissionPlease refer to "job Posting URL"Achievements and Activities : Online SubmissionPlease refer to "job Posting URL"Other online application forms
Please refer to "job Posting URL" -
Return of application documents
Others
Application documents will not be returned.
Submitted documents including personal information will be used only for the purpose of applicant screening.
URL of this job posting
Selection / Notification of result
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Selection
After a document screening, an interview examination will be conducted only for those who pass the screening.
A 20-minute presentation using materials will be held at the interview screening.
Content of the presentation: Self-introduction, research achievements, future research plans, one's aspirations -
Notification of result
The notification of hiring decision (conditional offer of employment) regarding this selection shall be carried out through the presentation of a Fixed-term Employment Contract or a Conditional Offer of Employment issued by RIKEN.
Contact details
RIKEN
Drug Discovery Genetically Modified Animal Platform Unit, BioResource Research Center, RIKEN
Unit Leader, Takanori Amano, Ph.D.
takanori.amano-ABC-(at)riken.jp
* Please change (at) to @ and send it.
Please send your inquiries by email. We will not take phone inquiries. Please use this subject line: Application for Postdoctoral Researcher or Research & Development Scientist, Drug Discovery Genetically Modified Animal Platform Unit (T25001)"
The above is "Inquiries regarding job duties".
For "Other inquiries" : brc-jinji-ABC-@ml.riken.jp
Notes
Handling Personal Data
Submitted documents are strictly protected under the RIKEN Privacy Policy and will be used only for the purpose of applicant screening at RIKEN. Personal information will not be disclosed, transferred or loaned to a third party under any circumstances without just cause.
Please delete "-ABC-" in the above email address.
